The popular drug Bravecto for dogs. Treatment and prevention of fleas and ticks. Composition and mechanism of action. How to use the drug correctly. Use of chewable tablets and solution. Advantages and disadvantages. Contraindications for use. Possible side effects. Reviews. Analogues of Bravecto.
We all know what troubles blood-sucking parasites can bring to our pets. Most often they are attacked by fleas and ticks, which are carriers of dangerous diseases. In addition, fleas inflict painful bites that cause severe itching.
Severe infection affects the general condition of the animal, they cannot rest, play, sleep normally, which causes a decrease in appetite, as a result of weight loss, the animal’s immune system suffers. Pets scratch their bites vigorously, resulting in wounds that can easily become infected.
Ticks are no less dangerous, since they can transmit an infection that leads to the development of severe diseases and will require long-term and difficult treatment. To avoid all these difficult situations, it is necessary to use specialized products that protect dogs from parasites.
One of these products is Bravecto, which is quite popular among dog breeders. It has a fairly wide spectrum of action, providing protection not only against ticks and fleas, but also other parasites. Next, we will take a closer look at the drug, learn about its features, advantages, contraindications, and also learn about its disadvantages.
Advantages of the drug
The drug has many advantages, including high efficiency and rapid action. After the tablet enters the pet’s body, the active ingredients begin to act within 2 hours. A wide spectrum of action, which makes it possible to get rid of fleas and protect the dog from parasites.
It comes in a very convenient form, in the form of chewable tablets, which in most cases dogs eat with pleasure, as they smell appetizing and taste good. They are available for sale in different forms, each containing a certain amount of the active ingredient. This allows you to purchase tablets with the correct dosage for large and small breeds.
Reception can be started at any time of the year, regardless of the season. Regarding the period for preventive purposes, the remedy can be taken from spring to autumn without interruption, when there is a danger of infection. But it must be given according to the regimen specified in the instructions, as well as the veterinarian’s recommendations; changing the treatment regimen is prohibited. This remedy has a prolonged effect. After administration, protection is provided for 12 weeks.
Important!
But remember that despite the huge number of benefits, use should only be done after consulting a doctor.
Bravecto instructions for use
Bravecto Spot On.
There are the following types of the drug:
- “Bravecto Spot On for dogs 112.5 mg” (Solution for spot application for dogs of very small breeds (2 - 4.5 kg));
- “Bravecto Spot On for dogs 250 mg” (Solution for spot application for small breed dogs (>4.5 - 10 kg));
- “Bravecto Spot On for dogs 500 mg” (Solution for spot application for dogs of medium breeds (>10 - 20 kg));
- “Bravecto Spot On for dogs 1000 mg” (Solution for spot application for large breed dogs (>20 - 40 kg));
- “Bravecto Spot On for dogs 1400 mg” (Solution for spot application for dogs of very large breeds (>40 - 56 kg));
- “Bravecto Spot On for cats 112.5 mg” (Solution for spot application for small breed cats (1.2 - 2.8 kg));
- “Bravecto Spot On for cats 250 mg” (Solution for spot application for cats of medium breeds (>2.8 - 6.25 kg));
- “Bravecto Spot On for cats 500 mg” (Solution for spot application for large breed cats (>6.25-12.5 kg)).
1.0 ml of the drug contains 280 mg of fluralaner and excipients up to 1 ml.
In appearance, the drug is a transparent solution from colorless to yellow.
Bravecto Spot It is produced in pipettes packaged in laminated aluminum sachets of 0.4 ml (Bravecto Spot It 112.5 mg, for small breed cats); 0.89 ml (Bravecto Spot On 250 mg, for medium breed cats); 1.79 ml (Bravecto Spot On 500 mg, for large breed cats); 0.4 ml (Bravecto Spot On 112.5 mg, for very small breed dogs); 0.89 ml (Bravecto Spot On 250 mg, for small breed dogs); 1.79 ml (Bravecto Spot On 500 mg, for medium breed dogs); 3.57 ml (Bravecto Spot On 1000 mg, for large breed dogs) and 5.0 ml (Bravecto Spot On 1400 mg, for very large breed dogs), closed with a high-density polyethylene cap. Pipettes are packaged in 1 or 2 pieces in cardboard boxes along with instructions for use.
The drug is stored in a place protected from direct sunlight, at a temperature from plus 2°C to plus 30°C. Do not freeze.
The shelf life of the drug is 2 years from the date of manufacture, subject to storage and transportation conditions.
Possible release forms
The product can be purchased not only in the form of tablets, but also as a solution. Each form has different types of release, which differ in the concentration of the active component and are presented in five different dosages. For small dogs weighing 4.6-10 kg, decorative 2-4.5 kg, medium 10-20 kg, large 21-40 kg, very large 41-56 kg.
Chewable tablets have an appetizing smell and taste of meat. They come in round shapes and are light or dark brown in color. Packed in blisters. One tablet is intended for one-time use. You cannot purchase a dosage for a large breed and divide it into portions for medium-sized ones. Used strictly for its intended purpose.
The solution is available in the form of a clear liquid, which may be colorless or have a yellow tint. The liquid is packaged in pipettes, which are also intended for single use.
Bravecto - composition
Dosage form: tablets for oral use. Bravecto is available in 5 dosages containing fluralaner as the active ingredient, in 1 tablet, respectively: 112.5 mg, 250 mg, 500 mg, 1000 mg or 1400 mg. In appearance, the drug is a round-shaped tablet from light brown to dark brown with a smooth or slightly rough surface, possibly containing inclusions. Bravecto is released packaged in 1 tablet in blisters made of aluminum foil, placed individually in cardboard packs along with instructions for use.
Composition and mechanism of action
Use is allowed only from the age of 8 weeks; in addition, the animal must weigh at least 2 kg. It is advisable to give the tablet with food. The main active component that has a detrimental effect on parasites is fluralaner. Once the parasite enters the body, it affects the nervous system. At first the parasite is paralyzed and cannot move, but soon dies.
The active substance is very dangerous for mammals, so its use must be carried out strictly according to the instructions for use. A single dose is calculated in such a way that it cannot harm the animal. Overdoses are very dangerous for the health and life of pets.
When a pet eats the medicine, it enters the stomach and quickly dissolves. The active substance accumulates in the tissues under the top layer of skin. When a pet is attacked by a flea or tick, poison inevitably enters their body. After administration, the active component is in the tissues and has an effect for 12 weeks. A flea, just like a tick, will die after the first bite.
Within 24 hours after administration, the maximum concentration of the substance is observed, which means that the dog is completely protected. The half-life is observed after 14 days, and remains at a constant concentration for 60 days, after which natural elimination begins, which continues for 14 weeks.
It is worth saying that the substance penetrates and accumulates not only in subcutaneous fat. They penetrate the kidneys, liver, muscle fibers and the maximum concentration is also observed in these organs. Therefore, the use of drugs with similar effects is prohibited, and in the case of the use of anthelmintic drugs, mandatory consultation with a veterinarian is required.
What is Bravecto for dogs?
The Intervet company (Netherlands) has developed an innovative drug that provides protection against 7 types of ticks and 2 types of fleas. Bravecto is intended for dogs and is created taking into account the biological characteristics of these pets. Chewable tablets are available in 5 dosages: 112.5, 250, 500, 1000, 1400 mg. The dose is selected individually depending on the size of the pet. In terms of the degree of impact on the body, the drug is classified as low-hazard and does not have mutagenic, teratogenic or embryotoxic effects.
Compound
Release form: flea and tick tablets for dogs. They come in light and dark brown colors. They have a pleasant smell and taste, so animals eat them with pleasure. The active substance is fluralaner. The drug also includes the following auxiliary components:
- Super Premium in Powder for Dog flavor;
- sucrose;
- sodium lauryl sulfate;
- disodium pamoate monohydrate;
- magnesium stearate;
- aspartame;
- glycerol;
- soybean oil;
- polyethylene glycol;
- corn starch.
Operating principle
Fluralaner blocks glutamate-dependent and GABA-dependent arthropod receptors, overstimulates neurons, disrupts the mechanism of transmission of nerve impulses, which leads to paralysis and death of parasites. Bravecto tablets are given orally, after which they are easily absorbed into the bloodstream. Within 1 day the maximum concentration of the active substance is observed, then for another 85 days an insectoacaricidal amount of fluralaner is present in the plasma. 100% of fleas die within 8 hours after ingestion, 99% of ticks die within 12 hours. Parasites do not develop resistance to the drug.
Advantages and disadvantages
The medicine Bravecto is a product of a leading European manufacturer. The company officially conducted research on more than 100 dogs, and the results were as follows:
- the drug is more effective than drugs based on permethrin, imidacloprid, fipronil;
- Bravecto can be given to puppies and lactating dogs;
- the medicine does not pose a threat to animals with a defect in the MDR-1 gene, brachycephals;
- allowed for puppies from 8 weeks in a five-fold dosage;
- begins to act within 2 hours after administration, protects the animal’s body from fleas and ticks for 12 weeks;
- Well tolerated by all breeds.
Any drug has its downsides, and Bravecto anti-tick tablets for dogs are no exception. Users note that the biggest drawback of the medicine is its high price. If you study real reviews, you can note that the tablet does not help all dogs and does not last as long as the manufacturer claims. After a while, the ticks “travel” through the animal and attach themselves to the skin. Some particularly picky pets do not want to eat Bravecto, so they have to force-feed the drug.
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Side effects
If you look at the information from the manufacturer, he assures that Bravecto can cause side effects only in very rare cases. But thanks to the reviews of those dog breeders who have already used the product, you can be convinced that the information from the manufacturer is not entirely true. Since many reviews say that there are a lot of side effects and quite often.
Quite often the dog experiences vomiting and loss of appetite. Less common is itching, hair loss, and diarrhea. The dog becomes lethargic, sleepy and tired, shows no interest in others, and refuses to play. Ulcers and scabs may appear.
These side effects are recorded by veterinarians, who are contacted by animal owners in case of side effects. An animal does not have all the symptoms at the same time; only 2-3 may be observed. If your pet has an individual intolerance to any components, side effects appear with the same symptoms.
It is worth saying that symptoms more often appear in small breed dogs when the dosage is incorrectly calculated. Most animals tolerate the product very well.
Side effects and overdose
Let's talk about what side effects Bravecto tablets can cause for dogs. Reviews from dog breeders, by the way, greatly expand this list compared to the official information from the instructions.
Thus, among the side effects, the manufacturer notes vomiting, increased salivation, decreased appetite, intestinal weakness, and lethargy. As for the reviews of the dog owners themselves, they add to this list various diseases of the gastrointestinal tract and poisoning of varying severity.
If your dog starts vomiting after taking the tablet, do not try to feed it the drug again. Perhaps in this way you will save her health.
In case of overdose, the animal is in a depressed mood and lacks appetite. The manufacturer promises that these symptoms will go away on their own.
What are the myths about the drug?
Since the product contains a potent toxic substance that accumulates in the dog’s body and remains there for quite a long time, the owners are quite wary of this point.
On the one hand, the product can protect against dangerous parasites; it is highly effective and quick-acting. But on the other hand, now you can find a huge number of reviews that talk about the negative impact of the substance on the animal’s body.
In fact, for a long time, Bravecto tablets have been the cause of controversy and discussion. A huge number of users on the Internet left reviews about the serious consequences that the drug caused.
Groups have been formed and a petition has been launched to get these pills taken off the market. The American Veterinary Association did not ignore this scandalous moment and independent studies were conducted. Studies have shown that Bravecto is safe.
Of course, the manufacturer is trying in every possible way to prove that its product is not dangerous. He collected the most common myths and gives comprehensive explanations that completely debunk them.
Myth 1
Causes severe complications including liver failure, cancer and blindness
- These diseases have no connection with taking the drug and the proof is laboratory tests. Some dogs do develop side effects, but this is due to individual intolerance to the substances that are included in the composition.
- In addition, all side effects manifest themselves in the form of a gastrointestinal upset, which most often goes away on its own and very quickly, without veterinary care. Data shows that side effects occur in only 5%. Other health problems and especially diseases are in no way related to taking the drug.
Myth 2
Health problems, including side effects, appear after long and regular use
- As we have already said, side effects develop due to individual intolerance. In turn, individual intolerance either exists or it does not; it cannot appear due to long-term use.
- This is a reaction of the body that does not want to take this or that component and this manifests itself from the first dose. Situations where similar symptoms were observed after long-term use were considered individually, and each was easy to explain.
- Most often, the drug was combined with other medications, which caused a reaction in the body. In addition, there are cases when the dosage was incorrectly selected; dogs can gain and lose weight, which in turn requires individual selection. The manufacturer insists on consulting a veterinarian before each use of Bravecto. Be sure to contact a veterinarian when taking other medications is required.
Myth 3
The growth of affected animals is recorded annually
- The fact is that in this case, the American agency, which carries out quality control for all groups of pharmaceuticals, helped debunk this myth. The classification of Bravecto, which indicates the development of side effects, is recorded as rare, which means that no more than 5% experience undesirable reactions of the body, most of which go away on their own.
- Regarding the growth of animals in which adverse reactions of the body have been noticed, this is indeed true, but this is not at all connected with the drug and its effect, but only with the large number of dogs who were given the medicine. If we talk about numbers, from 2014 to 2021 sales increased by 17 million doses, which was the reason for the increase, but, as before, the number does not exceed 5%.
Myths about the drug and their debunking
The manufacturer does not hide that the main active component of Bravecto is a pesticide that kills fleas and ticks by accumulating in animal tissues. Naturally, many owners are concerned that their pet will constantly have a small dose of a toxic drug in their blood.
It is around Bravecto that many years of controversy have been going on on the Internet. In contrast to the effectiveness and sustainable preservation of a high concentration of the active substance, there are numerous negative reviews. The anti-tick tablet for dogs, Bravecto, allegedly can cause serious harm even after one use. There are so many upset owners whose pets suffered serious complications after taking the pill that they create their own groups on social networks. And in 2015, an online petition was even created to remove Bravecto from production. In response to such massive actions, the American Veterinary Association conducted an independent study of the drug and confirmed the safety of the drug.
To reassure consumers, the manufacturer has compiled a list of the most common myths and debunked them.
Myth #1:
Bravecto provokes very serious health problems for the animal, including blindness, cancer, and liver failure.
Fact:
Clinical studies and analysis of veterinarian reports do not demonstrate a cause-and-effect relationship between Bravecto and the above pathologies. Indeed, some animals develop side effects or individual intolerance. But the percentage of such dogs is extremely small (about 5%), and the side effects themselves (usually gastrointestinal disorders) can be quickly eliminated even without contacting a veterinarian.
Myth #2:
Side effects from Bravecto may appear after several years of regular use.
Fact:
Individual intolerance appears immediately after taking the first tablet. The allergy cannot be acquired and appear several years after the animal regularly takes the tablets. However, the responsible manufacturer will thoroughly investigate every complaint received to ensure the safety of dogs regularly taking the drug. In most cases, “delayed” side effects develop as a result of combining Bravecto with other medications. It is also possible to develop unpleasant symptoms due to incorrect dosage. The fact is that a dog, like a person, can actively gain and lose weight. Therefore, before each use of Bravecto, you must consult a veterinarian or weigh the animal.
Myth #3:
Every year the number of animals affected by taking Bravecto increases exponentially.
Fact:
This myth was debunked not even by the manufacturer itself, but by the European Medicines Agency and the American Agency for Quality Control of Pharmaceutical Products. Based on veterinarian reports, it was concluded that the incidence of adverse side effects was classified as “rare.” This means that only 5% of animals may actually be affected by Bravecto. However, most side effects will not cause irreversible harm to the pet’s health.
As for the increase in the number of animals affected, this is indeed true. But such negative dynamics are not due to a deterioration in the quality of the drug, but to an increase in sales volume. More than 30 million doses of Bravecto were sold worldwide in 2016, up from 13 million in 2014. This positive sales trend reflects the confidence of both pet owners and veterinarians. Of course, the absolute number of dogs experiencing side effects has also increased. But the relative indicator has not changed. The number of victims still includes only 5% of animals.
Description of drops
Drops are intended for external use; they are produced in the form of a transparent liquid, which is packaged in special pipettes for one-time use. Just as in the case of tablets, the dosage is calculated for a certain weight of the dog. It would also be a good idea to contact a veterinarian, who will examine your pet, weigh it, and give recommendations regarding its intake.
Applying the drops is very convenient and easy, and is often a good alternative for those pets who refuse tablets. The cost of this form of release directly depends on the volume. But it is worth saying that drops are not as popular as tablets, so they cannot always be found in veterinary pharmacies.
The action of the drops is due to the active substance fluralaner. When the drops are applied to the skin, they penetrate the body and are carried throughout the body through the bloodstream. The active component accumulates in the epidermis and coat. The substance is eliminated from the body quite slowly, so the pet is protected throughout this time.
Correct Application
Drops can be used for treatment and as prevention against parasites. It must be applied by drop method directly to the skin. It is advisable to buy the dog a day or two before the appointment, but not use shampoo. After application, the animal should not be bathed, as this will significantly reduce the effectiveness. Regarding shampoo, it is an alkali, which also reduces the effect of the active substance.
When applying, the body must be dry. It is also prohibited to apply when there are injuries and wounds on the body. To do this, you need to part the fur and apply a few drops to the skin. It is very important to apply in such a way that your pet cannot lick them off. Therefore, it is applied to the withers area, between the shoulder blades and along the spine.
When Bravecto is used for treatment, it is applied once. If these are preventive measures, remember that the substances remain in the body for 12 weeks and provide protection; during this time, repeated application is prohibited; after the expiration of the period, a repeat procedure can be carried out.
Contraindications and side effects
Drops are considered safe drugs. Allowed for pregnant and lactating bitches. Puppies under 8 weeks of age are not allowed. Also, drops should not be used on animals whose weight is less than 1.2 kg. Contraindications also include individual intolerance to the components included in the composition.
Regarding adverse reactions of the body, they can occur due to individual intolerance. Itching, redness and irritation may appear on the skin. In such situations, the dog must be purchased using shampoo. If you experience any symptoms after bathing, be sure to contact your veterinarian.
Cost of the drug and analogues
As already mentioned, the cost will depend on the concentration of the active component. But the price is also affected by the place of sale, although there is no significant difference in price. The approximate cost of a tablet for one-time use will be from 1,400 to 1,900 rubles.
The cost is not the lowest, especially when compared with other drugs with the same effect. But here you should take into account the prolonged action. After all, most drugs provide protection for 1 month, while Bravecto lasts 3 months.
If for some reason you are looking for a replacement for Bravecto, there is a fairly large selection of drugs that can provide the same effect, but with a shorter period of time. Most often, products containing the active substances imidacloprid, fipronil, and permethrin are substitutes.
For example, you can purchase drugs that are also available in tablet form, these include:
- Frontline NexgarD. In this case, the action is carried out thanks to the substance afoxolaner. This allows you to provide protection against ectoparasites and helminths for 30 days. Dogs most often eat tablets that smell and taste like meat without much coaxing. The approximate cost of packaging is 1000-2000 rubles.
- Comfortis. Provides protection against ectoparasites, it contains spinosad, which has a similar effect as the substance in bravecto, but the difference is that it is excreted much faster, thereby not having such a long-lasting effect.
- Simparica. Contains the substance sarolaner, which is effective for 30-35 days. Available in liver flavor. You can buy a package for 1300-1800 rubles, which contains 3 tablets.
There are also analogues of Bravecto drops. These products have the same mechanism of action, but provide protection only for 1 month. These include Combo, Stronghold, Insectal, Brovex, Lawyer and others. Their cost is correspondingly less.
Let's sum it up
If we take into account the numerous reviews that talk about the dangers and serious consequences after taking Bravecto, then this certainly causes a lot of concern among dog breeders.
But if you study reliable information, you can make sure that the drug is not so dangerous and cannot lead to serious consequences. It is worth noting the advantages that Bravecto has, and this is, first of all, high efficiency and degree of protection for pets.
Regardless of which remedy you choose, be sure to consult a veterinarian.
Remember that these are toxic substances that are truly dangerous if used incorrectly. Source
INTERVET BRAVECTO 250 mg 4.5-10 kg insectoacaricidal tablet for dogs
COMPOSITION AND FORM OF RELEASE
Tablets for oral use Bravecto are available in 5 dosages containing fluralaner as the active ingredient, in 1 tablet respectively: 112.5 mg, 250 mg, 500 mg, 1000 mg or 1400 mg.
In appearance, the drug is a round-shaped tablet from light brown to dark brown with a smooth or slightly rough surface, possibly containing inclusions. Bravecto is released packaged in 1 tablet in blisters made of aluminum foil, placed individually in cardboard packs along with instructions for use.
PHARMACOLOGICAL PROPERTIES
Bravecto is an insectoacaricidal drug with systemic action. The fluralaner included in the drug is (4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-isoxazol-3-yl]-2-methyl-N-[2-oxo-2-(2 ,2,2-trifluoroethylamino) ethyl] benzamide) is an insectoacaricide of the isoxazoline group, active against fleas (Ctenocephalides felis and Ctenocephalides canis) and ixodid ticks (adults and larvae of Ixodes ricinus, Ixodes hexagonus, Ixodes scapularis, Ixodes holocyclus, Dermacentor retic ulatus, Dermacentor variabilis and Rhipicephalus sanguineus), parasitic on dogs. The mechanism of action of fluralaner is to block GABA-dependent and glutamate-dependent receptors of arthropods, hyperexcitation of neurons, disruption of the transmission of nerve impulses, which leads to paralysis and death of ectoparasites. After oral administration of the drug, fluralaner is easily absorbed from the gastrointestinal tract and reaches the systemic bloodstream, the maximum concentration in the blood plasma is achieved within 1 day, bioavailability is 20-27%, food intake accelerates absorption. Fluralaner is excreted slowly, mainly in unchanged form with feces (~90% of the dose) and partially with urine, the half-life is 12 days. The drug begins to act 4 hours after application and causes the death of fleas 8 hours after attachment to the host’s body, ticks - after 12 hours, preventing re-infestation of dogs with ectoparasites. The death of fleas occurs before laying eggs, which prevents contamination of premises with eggs and larvae.
In terms of the degree of impact on the body, Bravecto is classified as a “low-hazard” substance (hazard class 4 according to GOST 12.1.007-76); in recommended doses it does not have embryotoxic, teratogenic, or mutagenic effects.
INDICATIONS
Bravecto is prescribed to dogs for the treatment and prevention of aphanipterosis, in the complex therapy of allergic dermatitis caused by fleas, as well as acarosis caused by ixodid ticks.
DOSES AND METHOD OF APPLICATION
Bravecto is administered to dogs individually orally during or shortly before/after feeding at a therapeutic dose of 25-56 mg fluralaner per 1 kg of animal weight. Bravecto has an attractive aroma and taste and is generally readily eaten by dogs; otherwise, the drug is forcibly administered directly into the mouth or fed with food. Breaking tablets is not allowed. You should make sure that the dog has completely swallowed the required dose of the drug. The doses of the drug depending on the weight of the animal and the type of tablet used are presented in the table:
| Dog weight (kg) | Dose of active substance (mg/tablet) and number of tablets | ||||
| Bravecto 112.5 | Bravecto 250 | Bravecto 500 | Bravecto 1000 | Bravecto 1400 | |
| 2-4,5 | 1 | ||||
| >4,5-10 | 1 | ||||
| >10-20 | 1 | ||||
| >20-40 | 1 | ||||
| >40-56 | 1 | ||||
| >56 | A combination of two tablets is selected at the rate of 25-56 mg of fluralaner per 1 kg of animal weight | ||||
When using the drug in dogs weighing more than 56 kg, use a combination of tablets at the rate of 25-56 mg of fluralaner per 1 kg of animal weight. The drug can be used during pregnancy and lactation. Repeated treatments, if necessary, are carried out after 12 weeks.
Violations of the drug use regimen should be avoided, as this may lead to a decrease in its effectiveness. If the next treatment is missed, the use of the drug is resumed at the same dose according to the same regimen. No overdose symptoms were identified.
SIDE EFFECTS
Side effects and complications when using the drug in accordance with the instructions, as a rule, are not observed. In rare cases, vomiting, diarrhea, decreased appetite and drooling may occur. If your dog vomits within the first two hours after taking Bravecto, it is recommended to make sure that the vomiting has stopped and give the drug again at the same dose.
CONTRAINDICATIONS
Contraindication for use is individual intolerance to the components of the drug. The drug should not be used in puppies under 8 weeks of age and/or dogs weighing less than 2 kg.
Bravecto is not intended for use in food producing animals.
SPECIAL INSTRUCTIONS
No peculiarities of action were identified during the first use of the drug and when it was discontinued.
With the simultaneous use of Bravecto with anthelmintics, antibiotics, non-steroidal anti-inflammatory drugs and glucocorticosteroids, no adverse reactions or reduction in the effectiveness of the drug were detected.
STORAGE CONDITIONS
Store in sealed manufacturer's packaging, separate from food and feed, in a dry place, protected from light, inaccessible to children and animals, at a temperature from 0°C to 30°C. The shelf life of the medicinal product, subject to storage conditions, is 3 years from the date of production. Do not use Bravecto after the expiration date. Unused medicinal product is disposed of in accordance with legal requirements.
