Pets are the delight of city dwellers. Dogs and cats bring their owners a lot of joy. But they do not wash their paws with soap and can eat directly from the ground. It’s no wonder that pets get helminths from time to time. In a city apartment, close contact with cats and dogs cannot be avoided. Animals are picked up. Pets often love to snuggle in their owner's bed. Children play with them right on the floor. Pets need to undergo preventive cleansing of worms from time to time. The drug Milbemax will help relieve them of this problem.
When to use Milbemax?
Pets, no matter how well cared for, are at risk. It is easy for them to catch intestinal parasites. Close contact between people and animals can have unpleasant consequences - most helminths are dangerous to humans. Families with children should be especially careful.
Roundworms, tapeworms, flukes, and Giardia find shelter in the intestines of animals. More than a third of all known worms are dangerous to humans.
What to do? Should we really give up the pleasure of close communication with our four-legged friends? Of course not - it’s enough to take a responsible approach to the issue of preventing and treating helminthic infestations in them.
Pharmacological properties of the drug
Milbemax is a combined deworming drug that effectively eliminates intestinal parasites of various types in the body of animals.
The base substance of the medicine for worms, milbemycin oxime, belongs both to the group of antibiotics and anthelmintics. The substance effectively affects nematodes - parasites that inhabit the gastrointestinal tract of pets.
Helminths settle in the gastrointestinal tract of animals, but the larvae tend to penetrate both the blood and vital organs: the lungs. liver, kidneys. Milbemycin is able to penetrate the blood plasma and act on parasite larvae for several hours. After time, the active substance is completely eliminated from the body.
Praziquantel affects cestodes and nematodes. By influencing the cell membranes of parasites and their depolarization, the effect of destruction of flatworms is achieved. They die, are digested and leave the animal’s body. The peak concentration of the substance in the blood plasma occurs 1-4 hours after taking the tablet, then it is mobile and effectively biotransformed in the liver. It leaves the body with urine within 2 days.
It should be remembered that Milbemax is a moderately dangerous substance and belongs to hazard class III. The medicine is poisonous to aquarium fish, crustaceans and a number of other organisms adapted to life in water. The drug must be used strictly in doses so as not to harm the animal.
Details
Effect of the drug
All of the listed components of the tablets ensure effective ridding of parasites from the cat’s body. The active substances of Milbemax remove even helminth larvae from the cat’s body. Milbemycin affects the permeability of cell membranes, increasing it.
Thus, superpolarization of cell membranes occurs in muscle tissue, which paralyzes the worms and leads to their death.
The maximum effect of Milbemax is achieved within 2 hours; the substance is excreted in full in the urine 12 hours after taking the drug. The active ingredient praziquantel is effective in infecting animals with cestododes and nematodes.
Praziquantel increases the sensitivity of parasites to calcium ions, resulting in depolarization of the cell membrane, which leads to their destruction. The leaves die and leave the animal’s body naturally in the form of feces. Maximum concentration will require at least 1 hour; the substance is eliminated from the body within 2 hours.
Indications for use of milbemax
Milbemax is prescribed to cleanse the cat's body of parasites. Milbemax is effective against cestodiasis, nematosis, echinococcosis, dipylidia, toxocarozoa and hookworm. It is recommended to take the drug before vaccination.
Instructions. Treatment regimen
Milbemax is given to cats with food in a small amount of food so that it does not remain in the bowl. It is used once. Before treatment with Milbemax, it is recommended to fast. There is no need to use laxatives. To cleanse a cat's body of worms with one dose of Milbemax.
special instructions
It is not recommended to give Milbemax to cats weighing up to 0.5 kg, under 6 weeks of age, with impaired liver and kidney function, and if the cat has reduced immunity or an acute infection.
If you use it at an early age, you risk causing allergies and side effects in your cat. When a cat is pregnant, Milbemax tablets can be given only in the third trimester. During lactation, it is permissible to use Milbemax after 3 weeks after birth. Please consult your veterinarian first.
Side effects from taking Milbemax
Like any drug, Milbemax has side effects. Hazard class - 3. Milbemax does not cause teratogenic, embryotoxic, or sensitizing effects. Take the drug according to the manufacturer's recommendations and cats will respond well to the tablets. When taking Milbemax, the development of side effects is minimal.
As a rule, a negative reaction to taking the drug does not occur. Rarely, when the recommended dosage is exceeded, tremors, lethargy, and intestinal upset are observed. Stick to the indicated dosage and there will be no negative effects.
Composition and release form
Milbemax is available in several modifications:
- For puppies and small dogs, elongated tablets in a white coating with a transverse score are offered. On one side you can find the imprint “AA” and “NA”.
- For kittens and young cats, the drug is offered in tablet form in a beige-brown coating. The shape is elongated with beveled edges. In the middle there is a line and the imprints “BC” and “NA”.
- for dogs.
- for cats. The active ingredients of the drug are milbemycin and praziquantel. The drug goes on sale packaged in 2, 4, 10 tablets in one standard, and for dogs packages of up to one hundred tablets in a blister are offered. Blisters are packaged in cardboard boxes with a picture of the animal for which the drug is intended in a given dosage.
Release form and composition
Milbemax tablets are intended for deworming dogs. The parasites on which the drug acts do not bother the animal for a long time after treatment. The product is medicinal and prophylactic in case of infection with roundworms, whipworms, cystodes, tapeworms, and nematodes.
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The active ingredients are milbemycin oxime and praziquantel. There is a modification in tablets for puppies and small dogs, where the content of the main substance is 2.5 mg, and 25 mg of praziquantel, and there is also a drug on sale for large breeds of dogs, the ratio is different: 12.5 mg of milbemycin oxime and 125 mg praziquantel.
Auxiliary components: microcrystalline cellulose, croscarmellose sodium, povidone, lactose monohydrate, colloidal silicon and magnesium stearate.
Externally, these are long white tablets. The edges are beveled and there is a transverse notch on one side. Blisters contain two tablets.
Dosage
To correctly calculate the dosage, the age of the dog, its weight and information about previously given medications are important. Such data is needed due to the effect of some drugs on the activity of the gastrointestinal tract. This will not allow you to give the drug thoughtlessly, and, therefore, will eliminate the occurrence of a severe side effect of the drug Milbemax. Therefore, we study the instructions for use carefully!
The therapeutic dose starts with 0.5 mg of milbemycin oxime + 5 mg of praziquantel per 1 kg of animal weight. The table will help you calculate the dosage.
| Weight | Milbemax dosage (Puppies and small dog breeds), tablets |
| 0,5-1,0 | 0,5 |
| 1,0-5,0 | 1 |
| 5,0-10,0 | 2 |
| Milbemax (large breeds) | |
| 5,0-10,0 | 1 |
| 10,0-25,0 | 1 |
| 25,0-50,0 | 2 |
| 50,0-75,0 | 3 |
Symptoms of helminth infection in animals:
- passive, depressed state;
- complete refusal of food or, conversely, increased appetite;
- perversion of appetite (attempt to eat unsuitable objects, earth);
- dull coat;
- hair loss;
- crusts in the corners of the eyes;
- disruption of digestive processes (diarrhea, vomiting, constipation);
- blood in feces;
- signs of intestinal obstruction;
- rapid weight loss;
- barrel-shaped bloating;
- decreased immunity;
- pallor of the mucous membranes;
- growth retardation in puppies and kittens;
- convulsions as a result of general intoxication as a result of the activity of helminths;
- Sometimes you can see thin “worms” in the stool.
When should you not use Milbemax?
Milbemax is contraindicated in puppies of the following dog breeds:
- collie,
- bobtail,
- Sheltie
The reason is the increased sensitivity of animals of these breeds to the components of the drug.
It is not recommended to give the drug to puppies under 2 weeks of age or animals weighing less than 0.5 kg. Milbemax for dogs is intended for the treatment of animals weighing over 5 kg.
The drug is also not given to kittens under 6 weeks of age. Milbemax for young cats is not used for animals whose weight does not reach half a kilogram. Milbemax for cats is intended for animals weighing over 2 kg.
In addition, the drug is contraindicated in the following animals:
- exhausted;
- infected;
- with kidney diseases and liver damage;
- with an allergy to any component of the drug.
Instructions for use
Milbemax is used for pets of all breeds and ages. There is no need to put your pets on a starvation diet before using it. It will be enough to add tablets to the morning feed or force-feed. The dosage depends on the weight of the animal.
Milbemax dose for kittens and cats:
- kittens weighing from 0.5 to 1 kg are given half a pink tablet;
- kittens and cats weighing 1–2 kg – one pink tablet;
- for cats weighing 2–4 kg – half a red tablet;
- if the animal weighs from 4 to 8 kg - one red tablet;
- for large cats weighing from 8–12 kg – one and a half red tablets.
Pets should take the drug strictly according to the instructions. Before vaccination, cats and kittens are dewormed two weeks before vaccinations. As a preventative measure, it is recommended that pets take Milbemax every three months.
Dose for puppies and adult dogs:
- puppies weighing up to 1 kilogram require ½ children's tablet;
- puppies and adult small dogs weighing 1–5 kg – one tablet;
- puppies and large breed dogs weighing from 5 to 10 kg should be given two children's tablets;
- adult dogs weighing between 5 and 25 kg should take one adult tablet;
- larger dogs weighing 25–50 kg – two tablets;
- very large pets weighing from 50 to 75 kg – three adult tablets.
For treatment, Milbemax is used once a week for a month. For the purpose of prevention, the drug is taken once before the start of the summer season, and then monthly until the end of the season.
Dosage and rules of use
The anthelmintic agent is used once. Orally, with food. The intake should be monitored, as some animals refuse to take the medicine voluntarily. In these cases, it is necessary to place the tablet on the root of the tongue and hold the pet's mouth with your hands until the medicine is swallowed.
To avoid poisoning the animal, you should carefully consider the dosage of the drug.
Milbemax for kittens and young cats is taken:
0.5 tablets for animals weighing from 0.5 to 1 kg;
1 t. for cats weighing 1-2 kg.
Milbemax for cats:
0.5 tablets for animals weighing 2-4 kg;
1 t. – cats weighing 4-8 kg;
1.5 t. - cats weighing from 8 to 12 kg.
Milbemax for puppies and small breed dogs is given:
0.5 tablets for puppies weighing from 0.5 to 1 kg;
1 t. – dogs weighing from 1 to 5 kg;
2 tons – for animals weighing 5-10 kg.
Milbemax for adult dogs is used:
1 tablet – dogs weighing 5-25 kg;
2 tablets – for animals weighing 25-50 kg;
3 tablets – dogs from 50 to 75 kg.
Dosage
Milbemax is produced in tablets and has several varieties - depending on the concentration:
- 25 mg praziquantel, 2.5 mg milbemycin oxime - for puppies and small breed dogs;
- five times the dose of active ingredients (125 and 12.5 mg, respectively) - for animals weighing 5-25 kg.
Antiparasitic treatment of puppies must be carried out at 2, 4, 8 and 12 weeks. After a year, animals are treated quarterly. The standard dose is 5 mg of praziquantel and 0.5 mg of milbemycin oxime per 1 kg of pet’s body weight.
An individual treatment regimen is drawn up by a veterinarian; in the instructions, the manufacturer recommends the following method of application:
- for hookworm infection - 4 doses at weekly intervals, for prevention - monthly;
- for thelaziosis - once, in case of severe infection, the veterinarian may prescribe repeated treatment after 7 days;
- for the prevention of dirofilariasis - in the warm season - monthly.
Notes
Dogs affected by angiostrongylosis require 4 doses of the drug at weekly intervals.
In order to prevent dirofilariasis (in disadvantaged regions), Milbemax is taken in the warm season in places where vectors of infection (blood-sucking insects) appear. Once with the appearance of insects, and then at monthly intervals. Last application a month after the disappearance of mosquitoes and mosquitoes. Prevention of dirofilariasis requires consultation and observation of a specialist in order to exclude the presence of microfilariae in the animal’s blood.
Personal hygiene nuances
When giving medicine to an animal, it is necessary to comply with a number of hygienic requirements:
- When Milbemax is administered, smoking, eating or drinking is contraindicated.
- At the end of tactile contact with the medicine, you should wash your hands with soap.
- If the drug was taken by mistake by a person, you need to drink several glasses of warm water and seek help from medical specialists. To receive effective help, you must show the drug label, which lists the substances included in its composition.
- After the expiration date of the medicine, the packaging with unused tablets can simply be thrown away. No special measures are required to dispose of expired Milbemax.
General information
As with many other antiparasitic drugs, the effect of Milbemax is achieved due to the presence of milbemycin oxime and praziquantel in its composition. The tablets are oval in appearance, brown or light brown to beige.
There is a risk of rupture. Packaged in aluminum blisters. The blister contains two tablets, and the package contains 1 or 2 blisters.
The manufacturer novartis offers two versions of the drug:
- * for kittens dosage of 10 and 4 mg of praziquantel and milbemycin, respectively.
- * second form for large cats. The dosage of praziquantel reaches 40 mg, milbemycin 16 mg.
Milbemax also contains talc, microcrystalline cellulose, povidone, lactose, sodium carmellose, hypromellose, magnesium stearate. All listed components are auxiliary. The manufacturer adds colloidal silicon to Milbemax, as well as a food additive with beef flavor.
