Api-San Stop-Stress Drug for dogs up to 30 kg tab. No. 20 299911

Compound

Stop stress is a means to reduce excitability and correct psychogenic behavior disorders in dogs. He contains:

Phenibut is a derivative of aminobutyric acid, a substance that has sedative, anticonvulsant, muscle relaxant, and hypnotic effects;
Extracts of medicinal herbs.

The medicine is available in two forms: tablets and drops. The former may contain different amounts of active ingredients; for ease of dosage, tablets are available:

for large breed dogs: 1 tablet contains 250 mg of phenibut, 30 mg of plant extracts;
for medium and small animals – 100 mg of phenibut, 10 mg of natural components.

Drops contain 100 mg of active substance, 40 mg of valerian extract, 20 mg of other herbal extracts per 1 ml.

Herbal components that are part of the drug:

valerian rhizomes. They have sedative and antispasmodic effects, normalize sleep, and provide a stable sedative effect;
catnip (catnip). Has a calming effect, relieves stress;
motherwort grass. Calms, reduces nervous excitability, regulates the functional state of the central nervous system;
hop fruits. The plant is dangerous for dogs, it causes hyperthermia - a rapid increase in temperature, but in small quantities it calms;
Baikal skullcap. It is one of the most famous and effective medicinal plants known for its calming effects. It is useful for increased nervousness and excitability, accompanied by trembling, hypersensitivity of peripheral nerves.

Taken together, the components of the drug help reduce agitation and correct psychogenic behavioral disorders in animals.

Composition and release form

Stop-stress is produced by a Russian pharmaceutical company. It produces 2 forms of the drug: tablets and solution.

There are 2 types of Stop Stress tablets for dogs:

No. 2 (200 mg) for small and medium breeds weighing up to 30 kg, cost 245 rubles;
No. 5 (500 mg) for large and giant breeds weighing more than 30 kg, average price 315 rubles.

The solution (10%) is more popular with animal owners. It is equipped with a dispenser pipette, making it easier to use and calculate the required dosage. A 15 ml bottle costs an average of 215 rubles.

The composition and effect of the drugs are shown in the table:

Active substance	Effect	Presence (+)/absence (-) of a component
Active substance	Effect	Pills	Drops
Phenibut	Normalizes the processes of excitation and inhibition, improves cerebral circulation and metabolism. Relieves anxiety, improves sleep, removes aggression.	+	+
Baikal skull cap	Makes it easier to fall asleep, relieves anxiety and stress.	+	+
Peony	Improves oxygen supply to tissues and organs, relieves spasms, prevents seizures.	+	+
Motherwort	Relieves excitability and spasms, prevents convulsions, normalizes heart function.	+	+
Hop	Calms, improves sleep.	+	+
Valerian	Relaxes, relieves nervous tension and anxiety.	—	+
Mint	Improves the functioning of the central nervous system.	—	+

In combination, these components relieve anxiety and aggression, calm you down, help you relax and make it easier to endure stressful situations.

Purpose

Stop stress must be prescribed by a veterinarian and cannot be used for self-medication. Some components of the drug, despite their natural plant origin (including hops, valerian), can cause allergic reactions.

The medicine is prescribed:

with excessive nervous excitement;
to prevent motion sickness during transportation;
to prevent the negative consequences of factors irritating the nervous system.

In addition, veterinarians recommend using Stop-Stress when exposed to the following stress factors:

participation in exhibitions;
grooming;
visit to the veterinarian;
arrival of guests;
relocation, change of residence;
vaccination and others.

Dosage

Medicine with a sedative effect should be used as prescribed by a veterinarian.

Standard dosages:

to prevent stress - 3-5 days before the onset of an event that can provoke stress;
to prevent motion sickness of the pet in transport - immediately before the trip;
in case of increased sexual arousal - simultaneously with hormonal contraceptives prescribed by a veterinarian.

Important! The duration of the course and dosage are determined by the veterinarian individually, taking into account the signs of psychogenic behavioral disorders of the animal and the possible consequences of exposure to stress factors.

The medicine is given orally, on the root of the tongue, causing a swallowing reflex. Usually the daily dose is divided into morning and evening doses. The required amount is calculated based on the weight of the pet:

drops – 2 per 1 kg of body weight;
tablets - depending on the content of the active ingredient in the pills.

When using 100 mg tablets, the dosage is:

animal body weight – up to 5 kg – 1⁄4 tablet;
5-10 kg – 1⁄4-1/2 table;
10-20 kg – 1⁄2-1 table.

Daily dose when using 250 mg tablets (for large animals):

with a dog weighing 20-30 kg – 1⁄4-1/2 tablet;
30-40 kg – 1⁄2-1 tablet;
40-50 kg – 1 tablet;
more than 50 kg – 1-2 tables.

Instructions for use

To prevent motion sickness, the drug is given to the dog once 1–2 hours before the trip.

Stop stress in the form of tablets and drops is placed on the root of the tongue of dogs. It is allowed to use the product with a small amount of food, but there is a possibility that the pet will refuse the “seasoned” food.

The dosage of the drug, produced in liquid form, is used at the rate of 2 drops per 1 kg of dog weight. Dosage regimen: twice a day (morning and evening). The duration of use of the sedative is 2–3 weeks. If necessary, this period can be extended to 30 days.

To avoid stress during transportation, participation in exhibitions, and overexposure, Stop Stress begins to be used 4–5 days before the start of the expected event.

Tablet dosage regimen: table

Dog weight (kg)	Tablets 200 mg	Tablets 500 mg
5–10	0.25-0.5 tablets	—
10–20	0.5-1 tablet	—
20–30	1-1,5	0,25-0,5
30–40	1,5-2	0,5-1
40–50	—	1 tablet
50 or more	-—	1–2 tablets

The tablets are used in the same way as drops - twice a day for 15-21 days.

Possible side effects

Ordinary activated carbon can be used as a sorbent

There are no significant negative consequences for the dog's health. In rare cases, drowsiness and nausea may occur. Over time, these side effects go away on their own.

An overdose of the drug may cause indigestion, drowsiness, and nausea. In this case, the pet should be taken to the veterinarian for gastric lavage and sorbents.

When working with a sedative, you must follow the following safety rules:

refrain from smoking and eating;
be sure to wash your hands after giving the required dose to the dog;
owners of pets who have a personal intolerance to the components of the medicine should avoid direct contact with it;
Avoid using empty bottles for household purposes.

Restrictions

The herbal components of the drug can cause allergic reactions, so the medicine should not be used for animals with increased individual sensitivity. In addition, the ban applies to animals suffering from:

oncological diseases;
chronic pathologies of the genitourinary system;
diabetes mellitus

Important! Stop Stress should not be used by pregnant or lactating dogs.

If the drug is used for the first time, you need to monitor the animal’s condition: it may experience lethargy, drowsiness and nausea. This is not a pathology; such signs do not require medical intervention. Usually they go away on their own within a day or two. An overdose can cause negative reactions in a dog:

drowsiness;
vomiting;
intestinal disorder;
dysfunction of the liver, kidneys, and digestive system.

In such cases, it is necessary to urgently contact a veterinary clinic, where a specialist, after assessing the animal’s condition, will prescribe symptomatic therapy.

Stop-Stress Tablets 2 For Dogs Up to 30kg 20tab API-SAN

COMPOSITION AND FORM OF RELEASE

The drug contains as active ingredients phenibut (gamma-amino-beta-phenylbutyric acid hydrochloride) and a complex of aqueous extracts of medicinal plants (peony, Baikal skullcap, hops, motherwort, mint and valerian officinalis), as well as auxiliary components. It is a tablet for oral administration, weighing 200 mg. The drug is packaged in 20 tablets in polymer bottles with screw caps, which are packed in cardboard boxes.

PHARMACOLOGICAL PROPERTIES

Phenibut is a nootropic drug that facilitates GABA-mediated transmission of nerve impulses in the central nervous system. The drug has a tranquilizing, psychostimulating, antiplatelet and antioxidant effect, improves the functional state of the brain by normalizing tissue metabolism and a positive effect on cerebral circulation, by increasing the speed of blood flow and reducing vascular tone. Helps reduce or eliminate feelings of anxiety, restlessness, fear and hyperactive behavior in the animal, normalizes sleep, and has some anticonvulsant effect. Does not affect cholinergic and adrenergic receptors. Reduces the manifestations of asthenia and vasovegetative symptoms (irritability, aggression, sleep disturbance), has a corrective and regulatory effect on the processes of inhibition and excitation in the central nervous system. A complex of aqueous extracts of medicinal plants increases the body's adaptive capabilities to environmental stress factors. In terms of the degree of impact on the body of warm-blooded animals, the drug is classified as a moderately dangerous substance and in recommended doses does not have a locally irritating, resorptive-toxic, mutagenic, teratogenic or allergenic effect.

INDICATIONS

Prescribed to dogs of small and medium breeds (body weight up to 30 kg) to reduce and correct psychogenic behavioral disorders (increased excitability, fear, irritability and aggression, sleep disturbance). To increase the adaptive capabilities of the body and prevent stress during various activities and manipulations with animals (transportation, exhibitions, grooming, diagnostic studies, changing habitat and feeding ration, etc.).

DOSES AND METHOD OF APPLICATION

Stop stress tablets 200 mg are given orally to the animal individually with food or forcefully on the root of the tongue 2 times a day in doses according to the table:

Dog weight, kg	Amount of drug	Phenibut content, mg
5 − 10	¼ − ½ tablet	25 − 50
11 − 20	½ − 1	50 − 100
21 − 30	1 − 1½	100 − 150

The corrective treatment course for psychogenic behavioral disorders and increased excitability is on average 15–20 days, depending on the condition of the animal and the individual characteristics of the body, but no more than 4 weeks. In order to increase resistance to stress factors during various events, such as exhibitions, transportation, diagnostic studies, grooming, etc., the drug is prescribed 3 - 5 days before the intended manipulations and for 1 - 4 days after, depending on the type animal nervous system. To reduce increased sexual activity (excessive vocalization, restless behavior and aggression), the drug is recommended to be used simultaneously with hormonal contraceptives for animals according to the indicated doses. The duration of the course is determined by the veterinarian individually for a given animal.

SIDE EFFECTS

In very rare cases, with increased individual sensitivity to the components of the drug, the animal may experience vomiting, drowsiness, or, conversely, increased excitability and irritability, allergic reactions on the skin. If these signs appear, use of the drug should be discontinued.

CONTRAINDICATIONS

Individual hypersensitivity to the components of the drug. Pregnant and lactating bitches and animals under the age of 1 year cannot be treated. It is not recommended for use in dogs suffering from diabetes and diseases of the genitourinary system, as well as in animals with tumor lesions.

SPECIAL INSTRUCTIONS

No special precautions are required.

STORAGE CONDITIONS

With caution (list B). In a dry place, protected from direct sunlight and out of reach of children and animals. Separated from food and feed at temperatures from 0 to 25 °C. Shelf life: 2 years.

Weight: 0.2 kg.
Manufacturer: Russia