AVZ Dironet Deworming tablets for dogs of medium and large breeds (Code: 75096)

What kind of drug is this?

The drug is designed specifically for dogs of any age and any breed. It comes in three forms:

• pills;
• suspension;
• drops.

The veterinarian determines which form to choose. The purpose depends on the breed of the animal, age, type of parasites and other factors.

Does it help against worms?

It is used for the following purposes:

• prevention of helminthiasis;
• treatment of nematodes and cestodes at any stage of their development;
• prevention of dirofilariasis;
• destruction of fleas, lice, lice;
• preventing the appearance of demodectic and sarcoptoid mites.

Use the medicine according to the instructions in strictly defined doses.

Compound

Dironet is available in two types:

• for internal use;
• for external use.

The composition of the drug includes:

1. Pyrantel pamoate (150 mg). It creates a blockade of nerve impulses, thereby disrupting the activity of parasites, which leads to their death.
2. Ivermectin (0.06 mg). Destroys the muscle membrane of parasites. When the concentration of the substance reaches its maximum level, the parasite dies from paralysis.
3. Praziquantel (50 mg). Affects tapeworms.

The drops do not contain pyrantel pamoate, the remaining substances are identical.

Composition and pharmacological properties.

The drug as active ingredients in 1 ml, depending on the modification, respectively contains: “Dironet spot-on” for dogs – 85 mg of praziquantel and 20 mg of ivermectin, “Dironet spot-on” for cats – 85 mg of praziquantel and 5 mg of ivermectin, and also excipients.

"Dironet Spot-on" has a wide spectrum of antiparasitic action, is active against larval and mature stages of development of intestinal nematodes, including Toxocara canis, Toxocara cati, Toxascaris leonina, Ancylostoma spp., Uncinaria stenocephala, Trichuris vulpis, cestodes, including Echinococcus granulosus , Echinococcus multilocularis, diphyllobothrium Latum, Dipylidium caninum, MultiCeps multInia spp., Mesocestoides Lineatus, flea (ctenocephalides spp.), Lino (lino), lice (lino Gnatus setotus), Vrayeeds (Trichodectes canis), sarcoptoid (Sarcoptes Canis, Otodectes Cynotis, Notoedres Cati) and demodicosis (Demodex canis) mites that parasitize dogs and cats.

After cutaneous application, the drug, absorbed from the site of application, enters the systemic bloodstream, organs and tissues of the animal, providing an effective antiparasitic effect.

It has an insectoacaricidal effect on fleas, lice, lice, sarcoptic and demodectic mites that are present on animals at the time of treatment.

The mechanism of action of ivermectin, which is part of the drug, is its effect on the magnitude of the current of chlorine ions through the membranes of the nerve and muscle cells of the parasite. The main targets are glutamate-sensitive chloride channels, as well as gamma-aminobutyric acid receptors. A change in the current of chlorine ions disrupts the conduction of impulses, which leads to paralysis and death of ectoparasites and nematodes.

The mechanism of action of praziquantel is based on the depolarization of neuromuscular ganglion blockers, disruption of glucose transport and microtubular function of all phases of cestode development, which causes disruption of muscle innervation, paralysis and death of parasites.

Pills

The tablets are convenient to give to large breed dogs. The suspension is not very suitable in this case, since several syringes are required. The disadvantages are that capricious dogs may refuse to swallow it, then you will have to resort to some tricks.

Dosage

For the treatment of nematodes and cestodes, the dog is given 1 tablet per 10 kilograms of the animal’s weight. If the pet is over 60 kilograms, then a consultation is required before treatment.

Methods of application

Give the tablet strictly in the morning feeding. There is no need to adhere to special diets before deworming; laxatives should not be given to the animal either.

As a preventative measure, give tablets once every few months.

How to give the tablet:

• Crush the tablet and add it to the animal's food. Be sure to make sure your dog eats everything. Some animals smell the medicine and do not finish the food.
• Use an introducer .

For therapeutic purposes, the drug is taken once a month.

Instructions for use of Dironet for dogs

As a rule, in Dironet tablets for dogs, instructions for use are available in the form of an insert sheet or written on the packaging itself. But in case she got lost, below we told you how to properly give this drug to a dog.

Dironet tablets - instructions for use

Dironet tablets are given to the dog orally once during feeding in the morning along with a small amount of food, or they are injected directly onto the root of the tongue using a tablet dispenser. Dosage - 1 tablet per 10 kilograms of weight. Before using the drug, there is no need to use laxatives or fast. To prevent worms, Dironet is given once every three months.

To stop microfilariaemia, Dironet is given to a dog once a month, and for the purpose of prevention in regions unfavorable for this disease, the drug is used from April to November.

Dironet suspension - instructions for use

Dironet suspension, like tablets, is administered orally once (or administered onto the root of the tongue using a dispenser, or with a small amount of food during morning feeding). Dosage - 1 ml per 1 kilogram of weight. Before use, the bottle of suspension must be shaken well. A fasting diet or taking laxatives before using this anthelmintic is not required.

To prevent helminths, Dironet suspension is used once every three months. To prevent the appearance of microfilariae in the body - once 3-4 weeks.

Contraindications

This deworming remedy cannot be used in the following cases:

• pregnant and lactating bitches;
• puppies less than three weeks old;
• dogs suffering from infectious diseases.

Drops on the withers "Spot-On"

The advantage of the drug is that it fights not only internal parasites, but also those that live on the dog (fleas, lice, lice). The danger of drops is that the animal can lick them from the application site.

How to use:

1. Choose a place for application: spine, neck, shoulder blades.
2. Spread the fur and drip onto the skin in several places.
3. There should be no scratches or ulcers on the skin.
4. It is forbidden to bathe the dog for several days after the procedure.

Drops can only be used from two months of age. Dosage of the drug for puppies:

• up to 2 kg – 5 drops;
• 2-5 kg ​​– 0.5 ml;
• from 5 kg – 1 ml.

Dosage of the drug for adult dogs:

• 2-5 kg ​​– 1 ml;
• 5-10 kg – 2 ml;
• 10-20 kg – 4 ml;
• 20-30 kg – 6 ml.

If the animal is more than 30 kg, then the dose is calculated as follows: per 1 kg of body weight - 0.2 ml of the drug.

Doses and order of application.

The drug is used by animals by drip (“spot-on”) application to dry, intact skin.

Before use, break off the tip of the pipette tube and, spreading the fur, apply the drug to the animal’s skin along the spine, in places inaccessible for licking the drug - in the neck area at the base of the skull or between the shoulder blades.

When treating large animals, the contents of the pipettes are applied to the skin in 3–4 places.

The minimum therapeutic dose of the drug for adult animals is 0.2 ml/kg animal weight. The minimum therapeutic dose of the drug for puppies and kittens is 0.1 ml/kg body weight. Taking into account the type, age and weight of the animal being treated, a pipette tube of the required volume or a combination thereof is selected and the drug is used in the doses indicated in the table.

To destroy fleas, lice and lice, the animal is treated once, to prevent re-infestation - once a month throughout the entire season of insect activity.

To treat otodectosis (ear scabies), the drug is applied to the skin once. If necessary, the course of treatment is repeated after 1 month. During the treatment process, it is recommended to clean the ear canal of exudate and scabs, and in case of complications with otitis media, prescribe antimicrobial and anti-inflammatory drugs. For therapeutic purposes in cases of sarcoptic mange and demodicosis in dogs and notoedrosis in cats, the drug is used 2–4 times with an interval of 10–14 days until double negative results of acarological examination are obtained; in order to prevent possible invasion - 1 time per month. Treatment is recommended to be carried out comprehensively using etiotropic, pathogenetic and symptomatic drugs in accordance with the instructions for their use.

For deworming of animals with nematodes and cestodes of the gastrointestinal tract, the drug is used for therapeutic purposes once, for prophylactic purposes - once a quarter.

How to give the suspension?

The suspension is sold in bottles. The included measuring syringe is very convenient for dosing. It is very convenient to calculate the volume of the medicine, 1 ml of the product per 1 kg of animal weight.

Advantages of the suspension:

• Great for small breed dogs;
• It is convenient to administer to animals that have difficulty swallowing tablets.

There are no disadvantages; each owner chooses for himself the form of the drug that is convenient for him. The action and effectiveness of the suspension are similar to tablets.

"Junior" for puppies

Puppies can only use Dironet Junior. This drug is designed specifically for them. The active substances in the composition are the same as in Dironet, only in smaller quantities.

Dironet Junior is used for the treatment and prevention of nematodes in puppies and kittens from three weeks of age. The drug preserves the animal's immunity. It not only destroys helminths, but also restores damaged cells.

Dironet Junior is prescribed once in the morning feeding. It is produced in the form of a suspension, so it is very convenient to give it from a special dispenser syringe. 1 ml of suspension is measured per 1 kg of animal weight.

If the dog weighs less than 500 grams, then the measured dose is mixed with 30 ml of water and poured into the animal’s mouth. For preventive purposes, give the medicine once every few months. Take the drug seven days before vaccination.

Anthelmintic for dogs of medium breeds AVZ Dironet 500, 6 tab.

Dironet deworming tablets for dogs of medium breeds are a complex anthelmintic drug of a new generation. Advantages: • The widest spectrum of anthelmintic action. • High efficiency. • Convenient dosage for animals with different body weights. • An aromatic flavoring additive in the preparation: the taste of fresh meat for dogs and salmon for cats.

Composition and pharmacological properties. Dironet 500 tablets for dogs of medium breeds as active ingredients in 1 tablet contain pyrantel pamoate - 150 mg, praziquantel - 50 mg and ivermectin - 0.06 mg, as well as excipients. Dironet tablets are intended for dogs. Dironet 500 has a wide spectrum of nematocidal and cestodocidal action, is active against round and tape helminths parasitizing dogs and cats, including Toxocara canis, T. cati, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma caninum, Trichuris vulpis, Echinococcus granulosus , E. multilocularis, Diphyllobothrium latum, Dipylidium caninum, Multiceps multiceps, Taenia spp., as well as larval developmental phases (microfilaria) of Dirofilaria immitis and Dirofilaria repens. The mechanism of action of ivermectin is by binding to glutamate-dependent chloride channels located primarily in the swallowing and somatic muscles. As a result, the permeability of the membrane for chlorine ions increases, the transmission of neuromuscular impulses is blocked, paralysis and death of the parasite occurs. The mechanism of action of pyrantel pamoate is to block neuromuscular transmission, disrupt the permeability of cell membranes and inhibit cholinesterase, which also leads to paralysis and death of the parasite. The mechanism of action of praziquantel is based on disruption of glucose transport and microtubular function in cestodes, inhibition of fumarate reductase activity and ATP synthesis, increased permeability of cell membranes and disruption of muscle innervation.

Indications for use. Prevention of dirofilariasis, as well as treatment and prevention of nematodes and cestodiases in dogs and cats.

Contraindications. Do not use the drug together with piperazine derivatives, as well as pregnant and lactating animals, puppies and kittens under three weeks of age. For collie, sheltie and bobtail dogs, use the drug under the supervision of a doctor.

Doses and order of application. For nematodes and cestodes of the gastrointestinal tract: once, individually in the morning feeding, at a dose of 1 tablet per 10 kg of animal weight or 1 ml of suspension per 1 kg of animal weight. When deworming animals weighing less than 0.5 kg, immediately before use, add 0.3 ml of boiled water to the measured dose of the suspension, shake thoroughly and give to the animal orally. No preliminary fasting diet or use of laxatives is required. For preventive purposes, dogs and cats are dewormed quarterly at the above dose, as well as before each vaccination. To stop microfilariaemia in infected animals, the drug is prescribed in a therapeutic dose, once a month. In order to prevent dirofilariasis in dogs, Dironet is used in the spring-summer-autumn period: once before the start of mosquito flight (March-April), then monthly throughout the entire period from April to October, and the last time in the season - 1 month after end of mosquito flight (October-November).

Side effects. When using the drug according to the instructions, no side effects or complications are observed.

Storage. Dironet 500 and stored in the manufacturer's sealed packaging, protected from light and moisture, separate from food and feed, at a temperature of 0°C to 25°C, out of reach of children and animals.

Release form. Dironet 500 tablets for medium breed dogs - blisters of 6 tablets. Outer packaging: cardboard box.

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Large and small breeds

For dogs of large and small breeds, Dironet is available in different dosages. For collie, sheltie and bobtail dogs, use Dironet only under the supervision of a doctor .

What do "200" and "1000" mean?

In the pharmacy you can find packages of medicine with the numbers 200 and 1000 on them. This is the dosage of the drug for large and small breeds.

Dironet 200 is intended for puppies and small breed dogs. The dosage of the drug is 1 tablet per 4 kilograms of dog’s body weight.

Dironet 1000 is suitable for large breeds. It is calculated based on 1 tablet per 30 kilograms.

Dironet suspension for cats, 10 ml/pack, description

Properties

"Dironet" has a wide spectrum of action on all stages of development of round and tapeworms, incl.
Toxocara сanis, Toxocara сati, Toxassaris leоnina, Unсinaria stenocephala, Anсylostoma сaninum, Triсhuris vulpis, Eсhinososсus granulоsus, Eсhinososсus multiloсularis, Diphyllopothrium latum, Dipylidium сaninum, Multiсeps multiсeps, Taenia spp. and others. The drug has a detrimental effect on the microfilariae Dirofilaria immitis and D. repens in carnivores, and also prevents the development of microfilariae. The mechanism of action of ivermectin is by binding to glutamate-dependent chloride channels located primarily in the swallowing and somatic muscles. As a result, the permeability of the membrane for chlorine ions increases, the transmission of neuromuscular impulses is blocked, paralysis and death of the parasite occurs.

The mechanism of action of pyrantel pamoate is to block neuromuscular transmission, disrupt the permeability of cell membranes and inhibit cholinesterase, which also leads to paralysis and death of the parasite. The mechanism of action of praziquantel is based on disruption of glucose transport and microtubular function in cestodes, inhibition of fumarate reductase activity and ATP synthesis, increased permeability of cell membranes and disruption of muscle innervation.

Indications for use

Prevention of dirofilariasis, as well as treatment and prevention of nematodes and cestodiases in dogs and cats.

Dosage and method of administration

For nematodes and cestodes of the gastrointestinal tract: once, individually in the morning feeding, at a dose of 1 tablet per 10 kg of animal weight or 1 ml of suspension per 1 kg of animal weight. When deworming animals weighing less than 0.5 kg, immediately before use, add 0.3 ml of boiled water to the measured dose of the suspension, shake thoroughly and give to the animal orally. No preliminary fasting diet or use of laxatives is required. For preventive purposes, dogs and cats are dewormed quarterly at the above dose.

To stop microfilariaemia in infected animals, the drug is prescribed in a therapeutic dose, once a month. In order to prevent dirofilariasis in dogs, Dironet is used in the spring-summer-autumn period: once before the start of mosquito flight (March-April), then monthly throughout the entire period from April to October, and the last time in the season - 1 month after end of mosquito flight (October-November).

Side effects

When using the drug according to the instructions, no side effects or complications are observed.

Contraindications

Do not use the drug together with piperazine derivatives, as well as pregnant and lactating animals, puppies and kittens under three weeks of age. For collie, sheltie and bobtail dogs, use the drug under the supervision of a doctor.

Release form

“Dironet” suspension – 10 ml polymer bottle with a dispensing syringe; "Dironet" tablets - blisters of 6 tablets. Outer packaging: cardboard box.

Reviews

Owners

“I have a shepherd dog, she is already 8 years old. One day after a walk, I noticed her lethargic state; the next day she refused to walk at all. The veterinarian advised me to buy Dironet 1000, as she suggested that the reason for this behavior may lie in worms.

I gave medicine in the morning feeding. The dog ate it without any problems. The tablet has a meaty smell. By evening my pet returned to normal. Now I try to carry out prevention every quarter.”

“I have three dogs at home. All different breeds and ages. I always carry out deworming, but usually I used another remedy. My friends drew my attention to Dironet. The product is cheaper, but the effect is the same. I liked it, now we only use it.”

Veterinarians

“I used to prescribe Drontal or Cestal for parasites. Then she turned her attention to Dironet. It is very convenient that it comes in different forms. It can be used from three weeks of age. There are no side effects. It is important to measure the exact dose to prevent poisoning.”

“Dironet is excellent for preventing dirofilariasis. For puppies, I usually prescribe a more gentle remedy; I think that Dironet is not suitable for such babies, although it is allowed.”

What to replace it with?

The drug Dironet has several analogues:

1. Prazicide. The method of application and action are similar to the drug Dironet. The cost is slightly lower and is available in tablets and suspensions.
2. Milbemax. The drug is suitable for small breed dogs.
3. Dehinel Plus. Available only in tablet form. The drug has a pronounced taste of meat, dogs absorb it with pleasure without special tricks.
4. Vacation.

Before choosing analogues of the prescribed drug, make sure that the composition does not contain substances to which the dog may have an allergic reaction.